Four RCTs recruited people with a range of chronic wounds three RCTs recruited people with venous leg ulcers, and three RCTs considered foot ulcers in people with diabetes. The median number of participants per RCT was 29 (range 10 to 117). The search identified one new RCT, making a total of 10 included RCTs (442 participants, 42% women).
We used standard Cochrane methodology, including two reviewers independently selecting studies for inclusion, extracting data, and assessing risk of bias. We did not apply any date or language restrictions. We included randomised controlled trials (RCTs) that compared autologous PRP with placebo or alternative treatments for any type of chronic wound in adults.
We did not impose any restrictions with respect to language, date of publication, or study setting. We also searched for ongoing and unpublished clinical trials in the WHO International Clinical Trials Registry Platform (ICTRP) (searched January 2015). In June 2015, for this first update, we searched the Cochrane Wounds Specialised Register the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library): Ovid MEDLINE Ovid MEDLINE (In-Process & Other Non-Indexed Citations) Ovid EMBASE and EBSCO CINAHL. To determine whether autologous PRP promotes the healing of chronic wounds.
Roboform review 2016 update#
This is the first update of a review first published in 2012. Autologous platelet-rich plasma (PRP) is a treatment that contains fibrin and high concentrations of growth factors with the potential to improve the healing of chronic wounds.
0 kommentar(er)
